5HYT

Structure of human C4b-binidng protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M22 protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, G, E	Precursor to Protein Sir22	polymer	83	9865.8	4	UniProt (Q54901) In PDB	Streptococcus pyogenes
2	B, D, F, H	C4b-binding protein alpha chain	polymer	128	14163.9	4	UniProt (P04003) Pfam (PF00084) In PDB	Homo sapiens (Human)	C4bp,Proline-rich protein,PRP
3		water	water		18.0	70	Chemie (HOH)

Sequence modifications

A, C, G, E: 48 - 126 (UniProt: Q54901)

PDB	External Database	Details
Gly 44	-	expression tag
Pro 45	-	expression tag
Gly 46	-	expression tag
Ser 47	-	expression tag

B, D, F, H: 1 - 124 (UniProt: P04003)

PDB	External Database	Details
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	96118.8
All*	Total formula weight	96118.8

*Water molecules are not included.