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5HYT

Structure of human C4b-binidng protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M22 protein

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, F, H
(A, C, G, E)
Precursor to Protein Sir22polymer839865.84UniProt (Q54901)Streptococcus pyogenes
2B, D, E, G
(B, D, F, H)
C4b-binding protein alpha chainpolymer12814163.94UniProt (P04003)
Pfam (PF00084)
Homo sapiens (Human)C4bp,Proline-rich protein,PRP
3I, J, K, L, M...
(A, B, C, D, F...)
waterwater18.070Chemie (HOH)
Sequence modifications
A, C, G, E: 48 - 126 (UniProt: Q54901)
PDBExternal DatabaseDetails
Gly 44-expression tag
Pro 45-expression tag
Gly 46-expression tag
Ser 47-expression tag
B, D, F, H: 1 - 124 (UniProt: P04003)
PDBExternal DatabaseDetails
Gly -3-expression tag
Pro -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight96118.8
All*Total formula weight96118.8
*Water molecules are not included.

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PDB entries from 2025-12-17

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