5HYI
Glycosylated, disulfide-linked Hole-Hole Fc fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Ig gamma-1 chain C region | polymer | 227 | 25400.8 | 4 | UniProt (P01857) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
| 2 | E, F, G, H | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1625.5 | 4 | In PDB GlyTouCan (G27919IH) | |||
| 3 | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 221 - 447 (UniProt: P01857)
| PDB | External Database | Details |
|---|---|---|
| Cys 349 | Tyr 232 | engineered mutation |
| Ser 366 | Thr 249 | engineered mutation |
| Ala 368 | Leu 251 | engineered mutation |
| Val 407 | Tyr 290 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 101603.1 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 6502.0 | |
| All* | Total formula weight | 108105.1 |
