5HYE
Glycosylated Knob-Knob Fc fragment (P212121)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Ig gamma-1 chain C region | polymer | 227 | 25682.1 | 2 | UniProt (P01857) Pfam (PF07654) | Homo sapiens (Human) | |
| 2 | C, D (B, D) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1625.5 | 2 | In PDB GlyTouCan (G22043WL) | |||
| 3 | E, F (A, C) | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence modifications
A, C: 221 - 447 (UniProt: P01857)
| PDB | External Database | Details |
|---|---|---|
| Cys 354 | Ser 237 | engineered mutation |
| Trp 366 | Thr 249 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51364.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 3251.0 | |
| All* | Total formula weight | 54615.2 |
