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5HXH

Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with zero Na+ and Ca2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, Bsodium,calcium exchangerpolymer30032029.12UniProt (Q57556)
Pfam (PF01699)
In PDB
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
2A, BCALCIUM IONnon-polymer40.12Chemie (CA)
3A, BPENTAETHYLENE GLYCOLnon-polymer238.34Chemie (1PE)
4A, BPENTADECANEnon-polymer212.44Chemie (MYS)
5B(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoatenon-polymer356.52Chemie (OLC)
6waterwater18.039Chemie (HOH)
Sequence modifications
A, B: 1 - 300 (UniProt: Q57556)
PDBExternal DatabaseDetails
Val 2Leu 2engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight64058.3
Non-Polymers*Number of molecules12
Total formula weight2596.0
All*Total formula weight66654.3
*Water molecules are not included.

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PDB entries from 2024-06-26

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