5HX8
Jak1 complex with 4-[(4-aminocyclohexyl)amino]-3-(1H-benzimidazol-2-yl)-1H-pyridin-2-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Tyrosine-protein kinase JAK1 | polymer | 302 | 34746.6 | 2 | UniProt (P23458) Pfam (PF07714) In PDB | Homo sapiens (Human) | Janus kinase 1,JAK-1 |
| 2 | A, B | 4-[(4-aminocyclohexyl)amino]-3-(1H-benzimidazol-2-yl)-1H-pyridin-2-one | non-polymer | 323.4 | 2 | Chemie (66P) | |||
| 3 | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence modifications
A, B: 854 - 1154 (UniProt: P23458)
| PDB | External Database | Details |
|---|---|---|
| Gly 853 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69493.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 646.8 | |
| All* | Total formula weight | 70140.0 |
