5HVV
Crystal structure of Pro1 deletion and M2A double mutant of Macrophage Migration Inhibitory Factor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Macrophage migration inhibitory factor | polymer | 113 | 12197.8 | 3 | UniProt (P14174) Pfam (PF01187) | Homo sapiens (Human) | MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase |
| 2 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | E (B) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 4 | F, G, H (A, B, C) | water | water | 18.0 | 257 | Chemie (HOH) |
Sequence modifications
A, B, C: 2 - 114 (UniProt: P14174)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Met 3 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 36593.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 156.2 | |
| All* | Total formula weight | 36749.6 |
