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5HVE

5-methyl-6-(3'-trifluromethoxyphenylthio)[2,3-d]pyrimidine 2,4-diamine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dihydrofolate reductasepolymer18621349.51UniProt (P00374)
Pfam (PF00186)
Homo sapiens (Human)
2B
(A)
5-methyl-6-{[3-(trifluoromethoxy)phenyl]sulfanyl}thieno[2,3-d]pyrimidine-2,4-diaminenon-polymer372.41Chemie (65Q)
3C
(A)
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.41Chemie (NDP)
4D
(A)
waterwater18.0121Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight21349.5
Non-Polymers*Number of molecules2
Total formula weight1117.8
All*Total formula weight22467.3
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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