5HUI
6-substituted pyrido[3,2-d]pyrimidine--6-4'-trifluoromethoxyphenyl)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydrofolate reductase | polymer | 186 | 21349.5 | 1 | UniProt (P00374) Pfam (PF00186) | Homo sapiens (Human) | |
| 2 | B (A) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 3 | C (A) | N~6~-methyl-N~6~-[4-(trifluoromethoxy)phenyl]pyrido[3,2-d]pyrimidine-2,4,6-triamine | non-polymer | 350.3 | 1 | Chemie (65N) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E (A) | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21349.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1191.8 | |
| All* | Total formula weight | 22541.3 |
