5HTO

Crystal structure of Plasmodium Vivax LDH in complex with a DNA aptamer called pL1 (tetrameric LDH in an asymmetric unit)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, D, E (A, B, D, E)	L-lactate dehydrogenase	polymer	346	37659.7	4	UniProt (Q4PRK9)	Plasmodium vivax	Lactate dehydrogenase,Parasite lactate dehydrogenase
2	C (C)	DNA (34-MER)	polymer	34	10561.8	1		Plasmodium vivax
3	F (F)	DNA (30-MER)	polymer	30	9327.0	1		Plasmodium vivax
4	G, H (C, F)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	I, J, K, L, M... (A, B, C, D, E...)	water	water		18.0	898	Chemie (HOH)

Sequence modifications

A, B, D, E: 1 - 316 (UniProt: Q4PRK9)

PDB	External Database	Details
Met -29	-	expression tag
Gly -28	-	expression tag
Ser -27	-	expression tag
Ser -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
Ser -19	-	expression tag
Ser -18	-	expression tag
Gly -17	-	expression tag
Leu -16	-	expression tag
Val -15	-	expression tag
Pro -14	-	expression tag
Arg -13	-	expression tag
Gly -12	-	expression tag
Ser -11	-	expression tag
His -10	-	expression tag
Met -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	170527.4
Non-Polymers*	Number of molecules	2
	Total formula weight	48.6
All*	Total formula weight	170576.0

*Water molecules are not included.