5HT6

Crystal structure of the SET domain of the human MLL5 methyltransferase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Histone-lysine N-methyltransferase 2E	polymer	138	16107.5	2	UniProt (Q8IZD2) Pfam (PF00856)	Homo sapiens (Human)	Lysine N-methyltransferase 2E,Myeloid/lymphoid or mixed-lineage leukemia protein 5
2	C, D (A, B)	water	water		18.0	80	Chemie (HOH)

Sequence modifications

A, B: 20 - 155 (UniProt: Q8IZD2)

PDB	External Database	Details
Gly 18	-	expression tag
Pro 19	-	expression tag
Ala 150	Cys 453	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	32215.0
All*	Total formula weight	32215.0

*Water molecules are not included.