5HT6
Crystal structure of the SET domain of the human MLL5 methyltransferase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Histone-lysine N-methyltransferase 2E | polymer | 138 | 16107.5 | 2 | UniProt (Q8IZD2) Pfam (PF00856) In PDB | Homo sapiens (Human) | Lysine N-methyltransferase 2E,Myeloid/lymphoid or mixed-lineage leukemia protein 5 |
| 2 | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence modifications
A, B: 20 - 155 (UniProt: Q8IZD2)
| PDB | External Database | Details |
|---|---|---|
| Gly 18 | - | expression tag |
| Pro 19 | - | expression tag |
| Ala 150 | Cys 453 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32215.0 | |
| All* | Total formula weight | 32215.0 |
