5HSV
X-Ray structure of a CypA-Alisporivir complex at 1.5 angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Peptidyl-prolyl cis-trans isomerase A | polymer | 168 | 18318.8 | 4 | UniProt (P62938) Pfam (PF00160) | Chlorocebus aethiops (Green monkey) | PPIase A,Cyclophilin A,Cyclosporin A-binding protein,Rotamase A |
| 2 | E, F, G, H (E, F, G, H) | Alisporivir | polymer | 11 | 1232.6 | 4 | Tolypocladium inflatum | ||
| 3 | I, J, K, L (A, B, C) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 408 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 165 (UniProt: P62938)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 78205.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 141.8 | |
| All* | Total formula weight | 78347.5 |
