5HSV
X-Ray structure of a CypA-Alisporivir complex at 1.5 angstrom resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Peptidyl-prolyl cis-trans isomerase A | polymer | 168 | 18318.8 | 4 | UniProt (P62938) Pfam (PF00160) In PDB | Chlorocebus aethiops (Green monkey) | PPIase A,Cyclophilin A,Cyclosporin A-binding protein,Rotamase A |
2 | E, F, G, H | Alisporivir | polymer | 11 | 1232.6 | 4 | Tolypocladium inflatum | ||
3 | A, B, C | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
4 | water | water | 18.0 | 408 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 165 (UniProt: P62938)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 78205.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 141.8 | |
All* | Total formula weight | 78347.5 |