5HSV
X-Ray structure of a CypA-Alisporivir complex at 1.5 angstrom resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000413 | biological_process | protein peptidyl-prolyl isomerization |
| A | 0001933 | biological_process | negative regulation of protein phosphorylation |
| A | 0001934 | biological_process | positive regulation of protein phosphorylation |
| A | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| A | 0005178 | molecular_function | integrin binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006457 | biological_process | protein folding |
| A | 0006469 | biological_process | negative regulation of protein kinase activity |
| A | 0006915 | biological_process | apoptotic process |
| A | 0016018 | molecular_function | cyclosporin A binding |
| A | 0030168 | biological_process | platelet activation |
| A | 0030593 | biological_process | neutrophil chemotaxis |
| A | 0030595 | biological_process | leukocyte chemotaxis |
| A | 0032148 | biological_process | activation of protein kinase B activity |
| A | 0032873 | biological_process | negative regulation of stress-activated MAPK cascade |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| A | 0035307 | biological_process | positive regulation of protein dephosphorylation |
| A | 0042118 | biological_process | endothelial cell activation |
| A | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| A | 0043410 | biological_process | positive regulation of MAPK cascade |
| A | 0045069 | biological_process | regulation of viral genome replication |
| A | 0051092 | biological_process | positive regulation of NF-kappaB transcription factor activity |
| A | 0060352 | biological_process | cell adhesion molecule production |
| A | 0061944 | biological_process | negative regulation of protein K48-linked ubiquitination |
| A | 0070527 | biological_process | platelet aggregation |
| A | 1902176 | biological_process | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway |
| A | 1904399 | molecular_function | heparan sulfate binding |
| A | 2001233 | biological_process | regulation of apoptotic signaling pathway |
| B | 0000413 | biological_process | protein peptidyl-prolyl isomerization |
| B | 0001933 | biological_process | negative regulation of protein phosphorylation |
| B | 0001934 | biological_process | positive regulation of protein phosphorylation |
| B | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| B | 0005178 | molecular_function | integrin binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006457 | biological_process | protein folding |
| B | 0006469 | biological_process | negative regulation of protein kinase activity |
| B | 0006915 | biological_process | apoptotic process |
| B | 0016018 | molecular_function | cyclosporin A binding |
| B | 0030168 | biological_process | platelet activation |
| B | 0030593 | biological_process | neutrophil chemotaxis |
| B | 0030595 | biological_process | leukocyte chemotaxis |
| B | 0032148 | biological_process | activation of protein kinase B activity |
| B | 0032873 | biological_process | negative regulation of stress-activated MAPK cascade |
| B | 0034599 | biological_process | cellular response to oxidative stress |
| B | 0035307 | biological_process | positive regulation of protein dephosphorylation |
| B | 0042118 | biological_process | endothelial cell activation |
| B | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| B | 0043410 | biological_process | positive regulation of MAPK cascade |
| B | 0045069 | biological_process | regulation of viral genome replication |
| B | 0051092 | biological_process | positive regulation of NF-kappaB transcription factor activity |
| B | 0060352 | biological_process | cell adhesion molecule production |
| B | 0061944 | biological_process | negative regulation of protein K48-linked ubiquitination |
| B | 0070527 | biological_process | platelet aggregation |
| B | 1902176 | biological_process | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway |
| B | 1904399 | molecular_function | heparan sulfate binding |
| B | 2001233 | biological_process | regulation of apoptotic signaling pathway |
| C | 0000413 | biological_process | protein peptidyl-prolyl isomerization |
| C | 0001933 | biological_process | negative regulation of protein phosphorylation |
| C | 0001934 | biological_process | positive regulation of protein phosphorylation |
| C | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| C | 0005178 | molecular_function | integrin binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006457 | biological_process | protein folding |
| C | 0006469 | biological_process | negative regulation of protein kinase activity |
| C | 0006915 | biological_process | apoptotic process |
| C | 0016018 | molecular_function | cyclosporin A binding |
| C | 0030168 | biological_process | platelet activation |
| C | 0030593 | biological_process | neutrophil chemotaxis |
| C | 0030595 | biological_process | leukocyte chemotaxis |
| C | 0032148 | biological_process | activation of protein kinase B activity |
| C | 0032873 | biological_process | negative regulation of stress-activated MAPK cascade |
| C | 0034599 | biological_process | cellular response to oxidative stress |
| C | 0035307 | biological_process | positive regulation of protein dephosphorylation |
| C | 0042118 | biological_process | endothelial cell activation |
| C | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| C | 0043410 | biological_process | positive regulation of MAPK cascade |
| C | 0045069 | biological_process | regulation of viral genome replication |
| C | 0051092 | biological_process | positive regulation of NF-kappaB transcription factor activity |
| C | 0060352 | biological_process | cell adhesion molecule production |
| C | 0061944 | biological_process | negative regulation of protein K48-linked ubiquitination |
| C | 0070527 | biological_process | platelet aggregation |
| C | 1902176 | biological_process | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway |
| C | 1904399 | molecular_function | heparan sulfate binding |
| C | 2001233 | biological_process | regulation of apoptotic signaling pathway |
| D | 0000413 | biological_process | protein peptidyl-prolyl isomerization |
| D | 0001933 | biological_process | negative regulation of protein phosphorylation |
| D | 0001934 | biological_process | positive regulation of protein phosphorylation |
| D | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| D | 0005178 | molecular_function | integrin binding |
| D | 0005576 | cellular_component | extracellular region |
| D | 0005634 | cellular_component | nucleus |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006457 | biological_process | protein folding |
| D | 0006469 | biological_process | negative regulation of protein kinase activity |
| D | 0006915 | biological_process | apoptotic process |
| D | 0016018 | molecular_function | cyclosporin A binding |
| D | 0030168 | biological_process | platelet activation |
| D | 0030593 | biological_process | neutrophil chemotaxis |
| D | 0030595 | biological_process | leukocyte chemotaxis |
| D | 0032148 | biological_process | activation of protein kinase B activity |
| D | 0032873 | biological_process | negative regulation of stress-activated MAPK cascade |
| D | 0034599 | biological_process | cellular response to oxidative stress |
| D | 0035307 | biological_process | positive regulation of protein dephosphorylation |
| D | 0042118 | biological_process | endothelial cell activation |
| D | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| D | 0043410 | biological_process | positive regulation of MAPK cascade |
| D | 0045069 | biological_process | regulation of viral genome replication |
| D | 0051092 | biological_process | positive regulation of NF-kappaB transcription factor activity |
| D | 0060352 | biological_process | cell adhesion molecule production |
| D | 0061944 | biological_process | negative regulation of protein K48-linked ubiquitination |
| D | 0070527 | biological_process | platelet aggregation |
| D | 1902176 | biological_process | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway |
| D | 1904399 | molecular_function | heparan sulfate binding |
| D | 2001233 | biological_process | regulation of apoptotic signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 201 |
| Chain | Residue |
| A | GLY162 |
| A | GLN163 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 201 |
| Chain | Residue |
| B | ASP9 |
| B | GLY18 |
| B | ARG19 |
| B | HOH360 |
| D | PRO16 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 202 |
| Chain | Residue |
| B | LYS91 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue CL C 201 |
| Chain | Residue |
| C | GLY109 |
| C | SER110 |
| C | GLN111 |
| C | GLY74 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | binding site for residues BMT E 1 and MVA E 11 |
| Chain | Residue |
| A | ARG55 |
| A | PHE60 |
| A | GLN63 |
| A | ALA101 |
| A | ASN102 |
| A | ALA103 |
| A | PHE113 |
| A | HIS126 |
| A | HOH359 |
| E | ABA2 |
| E | DAM3 |
| E | 66E4 |
| E | VAL5 |
| E | MLE10 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | binding site for residues BMT E 1 and ABA E 2 |
| Chain | Residue |
| A | ARG55 |
| A | GLN63 |
| A | GLY72 |
| A | ALA101 |
| A | ASN102 |
| A | ALA103 |
| A | GLN111 |
| A | HOH359 |
| E | DAM3 |
| E | 66E4 |
| E | VAL5 |
| E | MLE10 |
| E | MVA11 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residues ABA E 2 and DAM E 3 |
| Chain | Residue |
| A | GLY72 |
| A | ALA101 |
| A | ASN102 |
| A | ALA103 |
| A | GLN111 |
| E | BMT1 |
| E | 66E4 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residues DAM E 3 and 66E E 4 |
| Chain | Residue |
| A | GLY72 |
| E | BMT1 |
| E | ABA2 |
| E | VAL5 |
| E | MLE6 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for Di-peptide 66E E 4 and VAL E 5 |
| Chain | Residue |
| A | ARG55 |
| E | BMT1 |
| E | DAM3 |
| E | MLE6 |
| E | HOH101 |
| E | HOH102 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for Di-peptide VAL E 5 and MLE E 6 |
| Chain | Residue |
| A | ARG55 |
| E | BMT1 |
| E | 66E4 |
| E | ALA7 |
| E | HOH101 |
| E | HOH102 |
| H | MLE6 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide MLE E 6 and ALA E 7 |
| Chain | Residue |
| E | 66E4 |
| E | VAL5 |
| E | DAL8 |
| E | HOH103 |
| H | MLE6 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for Di-peptide ALA E 7 and DAL E 8 |
| Chain | Residue |
| E | MLE6 |
| E | MLE9 |
| E | MLE10 |
| E | HOH103 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for Di-peptide DAL E 8 and MLE E 9 |
| Chain | Residue |
| A | PHE60 |
| A | TRP121 |
| E | ALA7 |
| E | MLE10 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residues MLE E 9 and MLE E 10 |
| Chain | Residue |
| A | ARG55 |
| A | PHE60 |
| A | TRP121 |
| E | BMT1 |
| E | DAL8 |
| E | MVA11 |
| site_id | AD6 |
| Number of Residues | 10 |
| Details | binding site for residues MLE E 10 and MVA E 11 |
| Chain | Residue |
| A | ARG55 |
| A | PHE60 |
| A | GLN63 |
| A | ALA101 |
| A | ASN102 |
| A | PHE113 |
| A | HIS126 |
| E | BMT1 |
| E | DAL8 |
| E | MLE9 |
| site_id | AD7 |
| Number of Residues | 13 |
| Details | binding site for residues BMT F 1 and MVA F 11 |
| Chain | Residue |
| B | HIS126 |
| B | HOH364 |
| F | ABA2 |
| F | DAM3 |
| F | 66E4 |
| F | VAL5 |
| F | MLE10 |
| B | ARG55 |
| B | GLN63 |
| B | ALA101 |
| B | ASN102 |
| B | ALA103 |
| B | PHE113 |
| site_id | AD8 |
| Number of Residues | 14 |
| Details | binding site for residues BMT F 1 and ABA F 2 |
| Chain | Residue |
| B | ARG55 |
| B | GLN63 |
| B | GLY72 |
| B | ALA101 |
| B | ASN102 |
| B | ALA103 |
| B | GLN111 |
| B | HOH364 |
| F | DAM3 |
| F | 66E4 |
| F | VAL5 |
| F | MLE10 |
| F | MVA11 |
| F | HOH102 |
| site_id | AD9 |
| Number of Residues | 10 |
| Details | binding site for residues ABA F 2 and DAM F 3 |
| Chain | Residue |
| B | GLY72 |
| B | ALA101 |
| B | ASN102 |
| B | ALA103 |
| B | GLN111 |
| F | BMT1 |
| F | 66E4 |
| F | HOH102 |
| F | HOH103 |
| F | HOH105 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residues DAM F 3 and 66E F 4 |
| Chain | Residue |
| B | GLY72 |
| F | BMT1 |
| F | ABA2 |
| F | VAL5 |
| F | MLE6 |
| F | HOH103 |
| F | HOH105 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for Di-peptide 66E F 4 and VAL F 5 |
| Chain | Residue |
| F | BMT1 |
| F | ABA2 |
| F | DAM3 |
| F | MLE6 |
| F | HOH101 |
| F | HOH104 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for Di-peptide VAL F 5 and MLE F 6 |
| Chain | Residue |
| F | BMT1 |
| F | 66E4 |
| F | ALA7 |
| F | HOH101 |
| F | HOH104 |
| G | MLE6 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for Di-peptide MLE F 6 and ALA F 7 |
| Chain | Residue |
| F | 66E4 |
| F | VAL5 |
| F | DAL8 |
| G | MLE6 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for Di-peptide ALA F 7 and DAL F 8 |
| Chain | Residue |
| F | MLE6 |
| F | MLE9 |
| F | MLE10 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for Di-peptide DAL F 8 and MLE F 9 |
| Chain | Residue |
| B | PHE60 |
| B | TRP121 |
| F | ALA7 |
| F | MLE10 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residues MLE F 9 and MLE F 10 |
| Chain | Residue |
| B | ARG55 |
| B | PHE60 |
| B | TRP121 |
| F | BMT1 |
| F | DAL8 |
| F | MVA11 |
| site_id | AE8 |
| Number of Residues | 10 |
| Details | binding site for residues MLE F 10 and MVA F 11 |
| Chain | Residue |
| B | ARG55 |
| B | PHE60 |
| B | GLN63 |
| B | ALA101 |
| B | ASN102 |
| B | PHE113 |
| B | HIS126 |
| F | BMT1 |
| F | DAL8 |
| F | MLE9 |
| site_id | AE9 |
| Number of Residues | 13 |
| Details | binding site for residues BMT G 1 and ABA G 2 |
| Chain | Residue |
| C | ARG55 |
| C | GLN63 |
| C | GLY72 |
| C | ALA101 |
| C | ASN102 |
| C | ALA103 |
| C | GLN111 |
| C | HOH363 |
| G | DAM3 |
| G | 66E4 |
| G | VAL5 |
| G | MLE10 |
| G | MVA11 |
| site_id | AF1 |
| Number of Residues | 14 |
| Details | binding site for residues BMT G 1 and MVA G 11 |
| Chain | Residue |
| C | ARG55 |
| C | PHE60 |
| C | GLN63 |
| C | ALA101 |
| C | ASN102 |
| C | ALA103 |
| C | PHE113 |
| C | HIS126 |
| C | HOH363 |
| G | ABA2 |
| G | DAM3 |
| G | 66E4 |
| G | VAL5 |
| G | MLE10 |
| site_id | AF2 |
| Number of Residues | 9 |
| Details | binding site for residues ABA G 2 and DAM G 3 |
| Chain | Residue |
| C | GLY72 |
| C | ALA101 |
| C | ASN102 |
| C | ALA103 |
| C | GLN111 |
| G | BMT1 |
| G | 66E4 |
| G | VAL5 |
| G | HOH101 |
| site_id | AF3 |
| Number of Residues | 6 |
| Details | binding site for residues DAM G 3 and 66E G 4 |
| Chain | Residue |
| C | GLY72 |
| G | BMT1 |
| G | ABA2 |
| G | VAL5 |
| G | MLE6 |
| G | HOH101 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide 66E G 4 and VAL G 5 |
| Chain | Residue |
| G | BMT1 |
| G | DAM3 |
| G | MLE6 |
| G | HOH102 |
| G | HOH103 |
| site_id | AF5 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide VAL G 5 and MLE G 6 |
| Chain | Residue |
| C | HOH351 |
| F | MLE6 |
| G | BMT1 |
| G | DAM3 |
| G | 66E4 |
| G | ALA7 |
| G | MLE10 |
| G | HOH102 |
| G | HOH103 |
| site_id | AF6 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide MLE G 6 and ALA G 7 |
| Chain | Residue |
| B | LYS125 |
| B | HOH358 |
| C | HOH351 |
| F | MLE6 |
| G | 66E4 |
| G | VAL5 |
| G | DAL8 |
| G | MLE10 |
| site_id | AF7 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide ALA G 7 and DAL G 8 |
| Chain | Residue |
| B | LYS125 |
| B | HOH358 |
| G | MLE6 |
| G | MLE9 |
| G | MLE10 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for Di-peptide DAL G 8 and MLE G 9 |
| Chain | Residue |
| C | PHE60 |
| C | TRP121 |
| G | ALA7 |
| G | MLE10 |
| site_id | AF9 |
| Number of Residues | 7 |
| Details | binding site for residues MLE G 9 and MLE G 10 |
| Chain | Residue |
| C | ARG55 |
| C | PHE60 |
| C | TRP121 |
| G | BMT1 |
| G | MLE6 |
| G | DAL8 |
| G | MVA11 |
| site_id | AG1 |
| Number of Residues | 11 |
| Details | binding site for residues MLE G 10 and MVA G 11 |
| Chain | Residue |
| C | ARG55 |
| C | PHE60 |
| C | GLN63 |
| C | ALA101 |
| C | ASN102 |
| C | PHE113 |
| C | HIS126 |
| G | BMT1 |
| G | MLE6 |
| G | DAL8 |
| G | MLE9 |
| site_id | AG2 |
| Number of Residues | 12 |
| Details | binding site for residues BMT H 1 and ABA H 2 |
| Chain | Residue |
| D | ARG55 |
| D | GLN63 |
| D | GLY72 |
| D | ALA101 |
| D | ASN102 |
| D | ALA103 |
| D | GLN111 |
| H | DAM3 |
| H | 66E4 |
| H | VAL5 |
| H | MLE10 |
| H | MVA11 |
| site_id | AG3 |
| Number of Residues | 13 |
| Details | binding site for residues BMT H 1 and MVA H 11 |
| Chain | Residue |
| D | ARG55 |
| D | PHE60 |
| D | GLN63 |
| D | ALA101 |
| D | ASN102 |
| D | ALA103 |
| D | PHE113 |
| D | HIS126 |
| H | ABA2 |
| H | DAM3 |
| H | 66E4 |
| H | VAL5 |
| H | MLE10 |
| site_id | AG4 |
| Number of Residues | 8 |
| Details | binding site for residues ABA H 2 and DAM H 3 |
| Chain | Residue |
| D | GLY72 |
| D | ALA101 |
| D | ASN102 |
| D | ALA103 |
| D | GLN111 |
| H | BMT1 |
| H | 66E4 |
| H | VAL5 |
| site_id | AG5 |
| Number of Residues | 7 |
| Details | binding site for Di-peptide 66E H 4 and VAL H 5 |
| Chain | Residue |
| D | ARG55 |
| H | BMT1 |
| H | DAM3 |
| H | MLE6 |
| H | HOH101 |
| H | HOH102 |
| H | HOH103 |
| site_id | AG6 |
| Number of Residues | 11 |
| Details | binding site for Di-peptide VAL H 5 and MLE H 6 |
| Chain | Residue |
| D | ARG55 |
| D | HOH259 |
| E | MLE6 |
| H | BMT1 |
| H | DAM3 |
| H | 66E4 |
| H | ALA7 |
| H | MLE10 |
| H | HOH101 |
| H | HOH102 |
| H | HOH103 |
| site_id | AG7 |
| Number of Residues | 7 |
| Details | binding site for Di-peptide MLE H 6 and ALA H 7 |
| Chain | Residue |
| D | HOH259 |
| E | MLE6 |
| H | 66E4 |
| H | VAL5 |
| H | DAL8 |
| H | MLE10 |
| H | HOH104 |
| site_id | AG8 |
| Number of Residues | 4 |
| Details | binding site for Di-peptide ALA H 7 and DAL H 8 |
| Chain | Residue |
| H | MLE6 |
| H | MLE9 |
| H | MLE10 |
| H | HOH104 |
| site_id | AG9 |
| Number of Residues | 4 |
| Details | binding site for Di-peptide DAL H 8 and MLE H 9 |
| Chain | Residue |
| D | PHE60 |
| D | TRP121 |
| H | ALA7 |
| H | MLE10 |
| site_id | AH1 |
| Number of Residues | 7 |
| Details | binding site for residues MLE H 9 and MLE H 10 |
| Chain | Residue |
| D | ARG55 |
| D | PHE60 |
| D | TRP121 |
| H | BMT1 |
| H | MLE6 |
| H | DAL8 |
| H | MVA11 |
| site_id | AH2 |
| Number of Residues | 11 |
| Details | binding site for residues MLE H 10 and MVA H 11 |
| Chain | Residue |
| D | ARG55 |
| D | PHE60 |
| D | GLN63 |
| D | ALA101 |
| D | ASN102 |
| D | PHE113 |
| D | HIS126 |
| H | BMT1 |
| H | MLE6 |
| H | DAL8 |
| H | MLE9 |
Functional Information from PROSITE/UniProt
| site_id | PS00170 |
| Number of Residues | 18 |
| Details | CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YkgScFHRIIpgFMcQGG |
| Chain | Residue | Details |
| A | TYR48-GLY65 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | MOD_RES: N-acetylmethionine => ECO:0000250|UniProtKB:P62937 |
| Chain | Residue | Details |
| A | MET1 | |
| B | MET1 | |
| C | MET1 | |
| D | MET1 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: N-acetylvaline; in Peptidyl-prolyl cis-trans isomerase A, N-terminally processed => ECO:0000250|UniProtKB:P62937 |
| Chain | Residue | Details |
| A | VAL2 | |
| B | VAL2 | |
| C | VAL2 | |
| D | VAL2 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | MOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:P62937 |
| Chain | Residue | Details |
| A | LYS28 | |
| A | LYS82 | |
| B | LYS28 | |
| B | LYS82 | |
| C | LYS28 | |
| C | LYS82 | |
| D | LYS28 | |
| D | LYS82 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P62937 |
| Chain | Residue | Details |
| A | LYS44 | |
| C | LYS76 | |
| C | LYS125 | |
| C | LYS131 | |
| D | LYS44 | |
| D | LYS76 | |
| D | LYS125 | |
| D | LYS131 | |
| A | LYS76 | |
| A | LYS125 | |
| A | LYS131 | |
| B | LYS44 | |
| B | LYS76 | |
| B | LYS125 | |
| B | LYS131 | |
| C | LYS44 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P62937 |
| Chain | Residue | Details |
| A | SER77 | |
| B | SER77 | |
| C | SER77 | |
| D | SER77 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P62937 |
| Chain | Residue | Details |
| A | THR93 | |
| B | THR93 | |
| C | THR93 | |
| D | THR93 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P17742 |
| Chain | Residue | Details |
| A | LYS133 | |
| B | LYS133 | |
| C | LYS133 | |
| D | LYS133 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN108 | |
| B | ASN108 | |
| C | ASN108 | |
| D | ASN108 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P62937 |
| Chain | Residue | Details |
| A | LYS28 | |
| B | LYS28 | |
| C | LYS28 | |
| D | LYS28 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0000250|UniProtKB:P62937 |
| Chain | Residue | Details |
| A | LYS82 | |
| B | LYS82 | |
| C | LYS82 | |
| D | LYS82 |
