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5HSR

Fluorine substituted 5-methyl-6-(3',4'-difluoromethoxyphenythio)thieno[2,3-d]pyrimidine-2,4-diamine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADihydrofolate reductasepolymer18621349.51UniProt (P00374)
Pfam (PF00186)
In PDB
Homo sapiens (Human)
2ANADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.41Chemie (NDP)
3A5-methyl-6-[(2,3,4-trifluorophenyl)sulfanyl]thieno[2,3-d]pyrimidine-2,4-diaminenon-polymer342.42Chemie (63Y)
4waterwater18.0188Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight21349.5
Non-Polymers*Number of molecules3
Total formula weight1430.1
All*Total formula weight22779.7
*Water molecules are not included.

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PDB entries from 2024-04-24

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