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5HS1

Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) complexed with Voriconazole

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Lanosterol 14-alpha demethylasepolymer52860587.71UniProt (A6ZSR0)
Pfam (PF00067)
Saccharomyces cerevisiae (Baker's yeast)
2B
(A)
PROTOPORPHYRIN IX CONTAINING FEnon-polymer616.51Chemie (HEM)
3C
(A)
Voriconazolenon-polymer349.31Chemie (VOR)
4D
(A)
waterwater18.0167Chemie (HOH)
Sequence modifications
A: 7 - 530 (UniProt: A6ZSR0)
PDBExternal DatabaseDetails
Gly 531-expression tag
Gly 532-expression tag
Arg 533-expression tag
His 534-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight60587.7
Non-Polymers*Number of molecules2
Total formula weight965.8
All*Total formula weight61553.5
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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