5HQP
Crystal structure of the ERp44-peroxiredoxin 4 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Peroxiredoxin-4 | polymer | 246 | 28007.5 | 2 | UniProt (Q13162) Pfam (PF00578) Pfam (PF10417) In PDB | Homo sapiens (Human) | Antioxidant enzyme AOE372,AOE37-2,Peroxiredoxin IV,Prx-IV,Thioredoxin peroxidase AO372,Thioredoxin-dependent peroxide reductase A0372 |
2 | C, D | Endoplasmic reticulum resident protein 44 | polymer | 382 | 44185.6 | 2 | UniProt (Q9BS26) Pfam (PF00085) Pfam (PF13848) In PDB | Homo sapiens (Human) | ERp44,Thioredoxin domain-containing protein 4 |
3 | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A, B: 38 - 271 (UniProt: Q13162)
C, D: 1 - 377 (UniProt: Q9BS26)
PDB | External Database | Details |
---|---|---|
Met 26 | - | expression tag |
Arg 27 | - | expression tag |
Gly 28 | - | expression tag |
Ser 29 | - | expression tag |
His 30 | - | expression tag |
His 31 | - | expression tag |
His 32 | - | expression tag |
His 33 | - | expression tag |
His 34 | - | expression tag |
His 35 | - | expression tag |
Gly 36 | - | expression tag |
Ser 37 | - | expression tag |
Ser 51 | Cys 51 | engineered mutation |
Ser 124 | Cys 124 | engineered mutation |
Glu 155 | Thr 155 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Pro -3 | - | expression tag |
Leu -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 144386.1 | |
All* | Total formula weight | 144386.1 |