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5HNM

Crystal structure of vancomycin resistance D,D-pentapeptidase VanY E175A mutant from VanB-type resistance cassette in complex with Zn(II)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
D-alanyl-D-alanine carboxypeptidasepolymer19722385.66UniProt (Q47746)
Pfam (PF02557)
Enterococcus faecalis (strain ATCC 700802 / V583)DD-peptidase
2G, I, K, L, M...
(A, B, C, D, E...)
ZINC IONnon-polymer65.46Chemie (ZN)
3H, J, N, P
(A, B, E, F)
SULFATE IONnon-polymer96.14Chemie (SO4)
4Q, R, S, T, U...
(A, B, C, D, E...)
waterwater18.0531Chemie (HOH)
Sequence modifications
A, B, C, D, E, F: 72 - 268 (UniProt: Q47746)
PDBExternal DatabaseDetails
Ala 175Glu 175engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight134313.7
Non-Polymers*Number of molecules10
Total formula weight776.7
All*Total formula weight135090.4
*Water molecules are not included.

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PDB entries from 2024-11-06

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