5HN8
Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH-1182
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Farnesyl pyrophosphate synthase, putative | polymer | 375 | 43784.2 | 4 | UniProt (A5K4U6) Pfam (PF00348) | Plasmodium vivax | |
| 2 | E, F, G, H (A, B, C, D) | 2-{[3-hydroxy-5-(octyloxy)benzyl]sulfanyl}benzoic acid | non-polymer | 388.5 | 4 | Chemie (HXK) PubChem (121595976) | |||
| 3 | I (D) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 161 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 22 - 396 (UniProt: A5K4U6)
| PDB | External Database | Details |
|---|---|---|
| Met 134 | Thr 113 | SEE REMARK 999 |
| Asp 227 | Asn 206 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 175136.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1650.1 | |
| All* | Total formula weight | 176786.9 |
