5HN7
Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH-1158
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Farnesyl pyrophosphate synthase, putative | polymer | 375 | 43784.2 | 8 | UniProt (A5K4U6) Pfam (PF00348) | Plasmodium vivax | |
| 2 | I, J, K, L, M... (A, B, C, D, E...) | 5-(morpholin-4-ylsulfonyl)-2-{[3-(octyloxy)benzyl]oxy}benzoic acid | non-polymer | 505.6 | 8 | Chemie (04M) | |||
| 3 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 1070 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 22 - 396 (UniProt: A5K4U6)
| PDB | External Database | Details |
|---|---|---|
| Met 134 | Thr 113 | SEE REMARK 999 |
| Asp 227 | Asn 206 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 350273.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 4045.0 | |
| All* | Total formula weight | 354318.5 |
