5HLY
Structure of Pro-Activin A Precursor at 2.3 A Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Inhibin beta A chain | polymer | 383 | 43664.0 | 1 | UniProt (P08476) Pfam (PF00688) Pfam (PF00019) | Homo sapiens (Human) | Activin beta-A chain,Erythroid differentiation protein,EDF,Pro-Activin A |
| 2 | B (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | C (A) | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence modifications
A: 30 - 426 (UniProt: P08476)
| PDB | External Database | Details |
|---|---|---|
| Mse 20 | - | initiating methionine |
| Ser 21 | - | expression tag |
| His 22 | - | expression tag |
| His 23 | - | expression tag |
| His 24 | - | expression tag |
| His 25 | - | expression tag |
| His 26 | - | expression tag |
| His 27 | - | expression tag |
| Ser 28 | - | expression tag |
| Mse 29 | - | expression tag |
| Ser 35 | Cys 35 | engineered mutation |
| Ser 38 | Cys 38 | engineered mutation |
| - | Lys 259 | deletion |
| - | Lys 260 | deletion |
| - | Lys 261 | deletion |
| - | Lys 262 | deletion |
| - | Lys 263 | deletion |
| - | Glu 264 | deletion |
| - | Glu 265 | deletion |
| - | Glu 266 | deletion |
| - | Gly 267 | deletion |
| - | Glu 268 | deletion |
| - | Gly 269 | deletion |
| - | Lys 270 | deletion |
| - | Lys 271 | deletion |
| - | Lys 272 | deletion |
| - | Gly 273 | deletion |
| - | Gly 274 | deletion |
| - | Gly 275 | deletion |
| - | Glu 276 | deletion |
| - | Gly 277 | deletion |
| - | Gly 278 | deletion |
| - | Ala 279 | deletion |
| - | Gly 280 | deletion |
| - | Ala 281 | deletion |
| - | Asp 282 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43664.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 43699.5 |
