5HL0
Crystal Structure of c-Cbl TKBD in complex with SPRY2 peptide (54-60, pY55) Refined to 2.2A Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase CBL | polymer | 308 | 35702.2 | 1 | UniProt (P22681) Pfam (PF02262) Pfam (PF02761) Pfam (PF02762) | Homo sapiens (Human) | Casitas B-lineage lymphoma proto-oncogene,Proto-oncogene c-Cbl,RING finger protein 55,Signal transduction protein CBL |
| 2 | B (B) | Sprouty 2 (SPRY2) | polymer | 8 | 901.8 | 1 | UniProt (by SIFTS) (O43597) | Homo sapiens | |
| 3 | C (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
A: 47 - 351 (UniProt: P22681)
| PDB | External Database | Details |
|---|---|---|
| Ser 44 | - | expression tag |
| Asn 45 | - | expression tag |
| Ala 46 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36604.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 23.0 | |
| All* | Total formula weight | 36627.0 |
