5HKO

Crystal structure of ABC transporter Solute Binding Protein MSMEG_3598 from Mycobacterium smegmatis str. MC2 155, target EFI-510969, in complex with L-sorbitol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	ABC transporter, carbohydrate uptake transporter-2 (CUT2) family, periplasmic sugar-binding protein	polymer	348	36654.9	1	UniProt (A0QYB3) Pfam (PF13407)	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)	Periplasmic sugar-binding proteins
2	B, C, D, E, F... (A)	ZINC ION	non-polymer		65.4	15	Chemie (ZN)
3	Q, R, S, T, U... (A)	CHLORIDE ION	non-polymer		35.5	9	Chemie (CL)
4	Z (A)	L-glucitol	non-polymer		182.2	1	Chemie (62W)
5	AA, BA, CA, DA, EA (A)	IMIDAZOLE	non-polymer		69.1	5	Chemie (IMD)
6	FA, GA, HA (A)	ACETATE ION	non-polymer		59.0	3	Chemie (ACT)
7	IA (A)	water	water		18.0	287	Chemie (HOH)

Sequence modifications

A: 25 - 349 (UniProt: A0QYB3)

PDB	External Database	Details
Met 2	-	initiating methionine
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
Ser 9	-	expression tag
Ser 10	-	expression tag
Gly 11	-	expression tag
Val 12	-	expression tag
Asp 13	-	expression tag
Leu 14	-	expression tag
Gly 15	-	expression tag
Thr 16	-	expression tag
Glu 17	-	expression tag
Asn 18	-	expression tag
Leu 19	-	expression tag
Tyr 20	-	expression tag
Phe 21	-	expression tag
Gln 22	-	expression tag
Ser 23	-	expression tag
Met 24	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36654.9
Non-Polymers*	Number of molecules	33
	Total formula weight	2004.9
All*	Total formula weight	38659.9

*Water molecules are not included.