5HKL

Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with inorganic phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Orotate phosphoribosyltransferase	polymer	190	20341.0	2	UniProt (P9WHK9) Pfam (PF00156)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	OPRTase
2	C (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
3	D, E (A, B)	water	water		18.0	208	Chemie (HOH)

Sequence modifications

A, B: 1 - 179 (UniProt: P9WHK9)

PDB	External Database	Details
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
Ile -4	-	expression tag
Glu -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	40682.0
Non-Polymers*	Number of molecules	1
	Total formula weight	95.0
All*	Total formula weight	40776.9

*Water molecules are not included.