5HKC
Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with 8-mer RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Endoribonuclease MazF6 | polymer | 114 | 12257.0 | 2 | UniProt (P9WII2) Pfam (PF02452) UniProt (by SIFTS) (P9WII3) | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) | Toxin MazF6,mRNA interferase MazF6 |
| 2 | C (C) | RNA (5'-R(*GP*UP*C)-D(P*U)-R(P*CP*CP*UP*A)-3') | polymer | 8 | 2447.5 | 1 | Mycobacterium tuberculosis | ||
| 3 | D, E, F (A, B, C) | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 114 (UniProt: P9WII2)
| PDB | External Database | Details |
|---|---|---|
| Asp 52 | Thr 52 | engineered mutation |
| Asp 62 | Phe 62 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 26961.6 | |
| All* | Total formula weight | 26961.6 |
