5HK3
Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Endoribonuclease MazF6 | polymer | 114 | 12257.0 | 2 | UniProt (P9WII3) Pfam (PF02452) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Toxin MazF6,mRNA interferase MazF-mt3 |
| 2 | C (C) | DNA (5'-D(*AP*GP*UP*CP*UP*CP*CP*UP*UP*UP*C)-3') | polymer | 11 | 3205.0 | 1 | Mycobacterium tuberculosis | ||
| 3 | D, E, F (A, B, C) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 114 (UniProt: P9WII3)
| PDB | External Database | Details |
|---|---|---|
| Asp 52 | Thr 52 | engineered mutation |
| Asp 62 | Phe 62 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 27719.1 | |
| All* | Total formula weight | 27719.1 |
