5HHF
Crystal structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant H63A with covalent FAD-Galactopyranose and bound UDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | UDP-galactopyranose mutase | polymer | 513 | 57061.4 | 4 | UniProt (Q4W1X2) Pfam (PF13450) | Neosartorya fumigata | |
| 2 | E, I, J, N, O... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 3 | F, K, R, W (A, B, C, D) | MESO-ERYTHRITOL | non-polymer | 122.1 | 4 | Chemie (MRY) | |||
| 4 | G, L (A, B) | [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S})-5-[5-[(2~{R},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-7,8-dimethyl-2,4-bis(oxidanyl)benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphate | non-polymer | 949.7 | 2 | Chemie (62F) | |||
| 5 | H, M (A, B) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
| 6 | S, X (C, D) | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE | non-polymer | 787.6 | 2 | Chemie (FDA) | |||
| 7 | AA, BA, Y, Z (C, D, A, B) | water | water | 18.0 | 740 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 510 (UniProt: Q4W1X2)
| PDB | External Database | Details |
|---|---|---|
| Ala -2 | - | expression tag |
| Ile -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ala 63 | His 63 | engineered mutation |
| Ala 344 | Lys 344 | engineered mutation |
| Ala 345 | Lys 345 | engineered mutation |
| Thr 429 | Ala 429 | see REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 228245.7 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 5732.0 | |
| All* | Total formula weight | 233977.7 |
