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5HGJ

Structure of integrin alpha1beta1 and alpha2beta1 I-domains explain differential calcium-mediated ligand recognition

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Integrin alpha-1polymer19521856.82UniProt (P56199)
Pfam (PF00092)
Homo sapiens (Human)CD49 antigen-like family member A,Laminin and collagen receptor,VLA-1
2C, F
(A, B)
CALCIUM IONnon-polymer40.12Chemie (CA)
3D
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
4E
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5G, H
(A, B)
waterwater18.0460Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight43713.5
Non-Polymers*Number of molecules4
Total formula weight207.7
All*Total formula weight43921.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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