5HGI
Crystal structure of apo human IRE1 alpha
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase/endoribonuclease IRE1 | polymer | 431 | 49303.3 | 1 | UniProt (O75460) Pfam (PF00069) Pfam (PF06479) | Homo sapiens (Human) | Endoplasmic reticulum-to-nucleus signaling 1,Inositol-requiring protein 1,hIRE1p,Ire1-alpha,IRE1a |
| 2 | B, C, D, E, F (A) | CESIUM ION | non-polymer | 132.9 | 5 | Chemie (CS) | |||
| 3 | G (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | H (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | I (A) | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 1 | Chemie (DTT) | |||
| 6 | J, K, L, M (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 4 | Chemie (BME) | |||
| 7 | N, O (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 8 | P (A) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 49303.3 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1317.3 | |
| All* | Total formula weight | 50620.6 |
