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5HGI

Crystal structure of apo human IRE1 alpha

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ASerine/threonine-protein kinase/endoribonuclease IRE1polymer43149303.31UniProt (O75460)
Pfam (PF00069)
Pfam (PF06479)
In PDB
Homo sapiens (Human)Endoplasmic reticulum-to-nucleus signaling 1,Inositol-requiring protein 1,hIRE1p,Ire1-alpha,IRE1a
2ACESIUM IONnon-polymer132.95Chemie (CS)
3ASODIUM IONnon-polymer23.01Chemie (NA)
4AGLYCEROLnon-polymer92.11Chemie (GOL)
5A2,3-DIHYDROXY-1,4-DITHIOBUTANEnon-polymer154.31Chemie (DTT)
6ABETA-MERCAPTOETHANOLnon-polymer78.14Chemie (BME)
7ACHLORIDE IONnon-polymer35.52Chemie (CL)
8waterwater18.010Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight49303.3
Non-Polymers*Number of molecules14
Total formula weight1317.3
All*Total formula weight50620.6
*Water molecules are not included.

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PDB entries from 2024-06-12

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