5HG1
Crystal Structure of Human Hexokinase 2 with cmpd 1, a C-2-substituted glucosamine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Hexokinase-2 | polymer | 922 | 102945.3 | 1 | UniProt (P52789) Pfam (PF00349) Pfam (PF03727) In PDB | Homo sapiens (Human) | Hexokinase type II,HK II,Muscle form hexokinase |
2 | A | 2-deoxy-2-{[(2E)-3-(3,4-dichlorophenyl)prop-2-enoyl]amino}-alpha-D-glucopyranose | non-polymer | 378.2 | 2 | Chemie (62C) | |||
3 | A | 6-O-phosphono-beta-D-glucopyranose | non-polymer | 260.1 | 1 | Chemie (BG6) | |||
4 | A | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
5 | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: 17 - 916 (UniProt: P52789)
PDB | External Database | Details |
---|---|---|
Met -5 | - | initiating methionine |
Gly -4 | - | expression tag |
Ser -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
His 1 | - | expression tag |
His 2 | - | expression tag |
His 3 | - | expression tag |
His 4 | - | expression tag |
Ser 5 | - | expression tag |
Ser 6 | - | expression tag |
Gly 7 | - | expression tag |
Leu 8 | - | expression tag |
Glu 9 | - | expression tag |
Asn 10 | - | expression tag |
Leu 11 | - | expression tag |
Tyr 12 | - | expression tag |
Phe 13 | - | expression tag |
Gln 14 | - | expression tag |
Gly 15 | - | expression tag |
Ser 16 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 102945.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1205.6 | |
All* | Total formula weight | 104151.0 |