5HEL
Crystal structure of the N-terminus Y153H bromodomain mutant of human BRD2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 2 | polymer | 126 | 14891.4 | 1 | UniProt (P25440) Pfam (PF00439) | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
| 2 | B, C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 3 | E (A) | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A: 71 - 194 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Ser 69 | - | expression tag |
| Met 70 | - | expression tag |
| His 153 | Tyr 153 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14891.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 186.2 | |
| All* | Total formula weight | 15077.6 |
