5HCA

Globular Domain of the Entamoeba histolytica calreticulin in complex with glucose

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (C, A, B)	Calreticulin,Calreticulin	polymer	274	31471.2	3	UniProt (F2VN92) Pfam (PF00262) UniProt (by SIFTS) (P83003)	Entamoeba histolytica HM-1:IMSS
2	D, I, O (C, A, B)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
3	E, G, H, M, N (C, A, B)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
4	F (A)	AMMONIUM ION	non-polymer		18.0	1	Chemie (NH4)
5	J, P (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6	K (A)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
7	L (A)	beta-D-glucopyranose	non-polymer		180.2	1	Chemie (BGC)
8	Q, R, S (C, A, B)	water	water		18.0	255	Chemie (HOH)

Sequence modifications

C, A, B: 13 - 203 (UniProt: F2VN92)

PDB	External Database	Details
Met 12	-	initiating methionine

C, A, B: 289 - 360 (UniProt: F2VN92)

PDB	External Database	Details
Gly 204	-	linker
Ser 205	-	linker
Gly 206	-	linker
Gly 361	-	expression tag
His 362	-	expression tag
His 363	-	expression tag
His 364	-	expression tag
His 365	-	expression tag
His 366	-	expression tag
His 367	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	94413.6
Non-Polymers*	Number of molecules	13
	Total formula weight	928.7
All*	Total formula weight	95342.3

*Water molecules are not included.