5H4D
Crystal structure of hSIRT3 in complex with a specific agonist Amiodarone hydrochloride
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, H | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | polymer | 271 | 30195.8 | 2 | UniProt (Q9NTG7) Pfam (PF02146) In PDB | Homo sapiens (human) | hSIRT3,Regulatory protein SIR2 homolog 3,SIR2-like protein 3 |
| 2 | D, C | ARG-HIS-LYS | polymer | 4 | 612.7 | 2 | Homo sapiens | ||
| 3 | A, H | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | A, H | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | A, H | (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone | non-polymer | 645.3 | 2 | Chemie (BBI) | |||
| 6 | A, H | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 7 | D, C | 7-AMINO-4-METHYL-CHROMEN-2-ONE | non-polymer | 175.2 | 2 | Chemie (MCM) | |||
| 8 | H | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 61617.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3359.5 | |
| All* | Total formula weight | 64976.7 |
