Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0017136 | molecular_function | NAD-dependent histone deacetylase activity |
A | 0051287 | molecular_function | NAD binding |
A | 0070403 | molecular_function | NAD+ binding |
H | 0017136 | molecular_function | NAD-dependent histone deacetylase activity |
H | 0051287 | molecular_function | NAD binding |
H | 0070403 | molecular_function | NAD+ binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue ZN A 401 |
Chain | Residue |
A | CYS256 |
A | CYS259 |
A | CYS280 |
A | CYS283 |
site_id | AC2 |
Number of Residues | 9 |
Details | binding site for residue BBI A 403 |
Chain | Residue |
D | ARG1 |
D | HIS2 |
H | PRO326 |
H | SER329 |
A | PHE157 |
A | ARG158 |
A | GLU177 |
A | PHE294 |
A | VAL324 |
site_id | AC3 |
Number of Residues | 17 |
Details | binding site for residue NAD A 404 |
Chain | Residue |
A | GLY145 |
A | ALA146 |
A | GLY147 |
A | SER149 |
A | THR150 |
A | PHE157 |
A | ARG158 |
A | GLN228 |
A | ASN229 |
A | ILE230 |
A | ASP231 |
A | HIS248 |
A | GLY319 |
A | THR320 |
A | SER321 |
A | ASP365 |
A | VAL366 |
site_id | AC5 |
Number of Residues | 7 |
Details | binding site for residue PEG H 401 |
Chain | Residue |
H | ARG224 |
H | ALA241 |
H | SER242 |
H | LYS243 |
H | LEU244 |
H | VAL245 |
H | ARG301 |
site_id | AC6 |
Number of Residues | 4 |
Details | binding site for residue ZN H 402 |
Chain | Residue |
H | CYS256 |
H | CYS259 |
H | CYS280 |
H | CYS283 |
site_id | AC7 |
Number of Residues | 8 |
Details | binding site for residue BBI H 405 |
Chain | Residue |
A | PRO326 |
A | SER329 |
C | ARG1 |
H | ARG158 |
H | GLU177 |
H | PHE294 |
H | VAL324 |
H | NAD406 |
site_id | AC8 |
Number of Residues | 18 |
Details | binding site for residue NAD H 406 |
Chain | Residue |
H | GLY145 |
H | ALA146 |
H | GLY147 |
H | SER149 |
H | THR150 |
H | PRO151 |
H | ARG158 |
H | GLN228 |
H | ASN229 |
H | ILE230 |
H | ASP231 |
H | HIS248 |
H | THR320 |
H | SER321 |
H | ASN344 |
H | ASP365 |
H | VAL366 |
H | BBI405 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | HIS248 | |
H | HIS248 | |
Chain | Residue | Details |
A | GLY145 | |
A | GLN228 | |
A | GLY319 | |
A | ASN344 | |
H | GLY145 | |
H | GLN228 | |
H | GLY319 | |
H | ASN344 | |
Chain | Residue | Details |
A | CYS256 | |
A | CYS259 | |
A | CYS280 | |
A | CYS283 | |
H | CYS256 | |
H | CYS259 | |
H | CYS280 | |
H | CYS283 | |
Chain | Residue | Details |
A | LYS122 | |
H | LYS122 | |