5H31
Structural basis for dimerization of the death effector domains of Caspase-8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Caspase-8 | polymer | 188 | 22342.8 | 4 | UniProt (Q14790) Pfam (PF01335) In PDB | Homo sapiens (Human) | CASP-8,Apoptotic cysteine protease,Apoptotic protease Mch-5,CAP4,FADD-homologous ICE/ced-3-like protease,FADD-like ICE,FLICE,ICE-like apoptotic protease 5,MORT1-associated ced-3 homolog,MACH |
Sequence modifications
A, B, C, D: 1 - 188 (UniProt: Q14790)
| PDB | External Database | Details |
|---|---|---|
| Ala 122 | Phe 122 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 89371.3 | |
| All* | Total formula weight | 89371.3 |
