5H13
EED in complex with PRC2 allosteric inhibitor EED396
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polycomb protein EED | polymer | 376 | 43434.5 | 1 | UniProt (O75530) Pfam (PF00400) | Homo sapiens (Human) | hEED,WD protein associating with integrin cytoplasmic tails 1,WAIT-1 |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | PRASEODYMIUM ION | non-polymer | 140.9 | 1 | Chemie (PR) | |||
| 4 | D (A) | 4-azanylidene-2-(3-methoxy-4-propan-2-yloxy-phenyl)-6,7-dihydro-[1,3]benzodioxolo[6,5-a]quinolizine-3-carbonitrile | non-polymer | 429.5 | 1 | Chemie (LQA) | |||
| 5 | E (A) | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A: 76 - 441 (UniProt: O75530)
| PDB | External Database | Details |
|---|---|---|
| Gly 66 | - | expression tag |
| Ile 67 | - | expression tag |
| Leu 68 | - | expression tag |
| Glu 69 | - | expression tag |
| Asn 70 | - | expression tag |
| Leu 71 | - | expression tag |
| Tyr 72 | - | expression tag |
| Phe 73 | - | expression tag |
| Gln 74 | - | expression tag |
| Gly 75 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43434.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 662.5 | |
| All* | Total formula weight | 44096.9 |
