5H13
EED in complex with PRC2 allosteric inhibitor EED396
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Polycomb protein EED | polymer | 376 | 43434.5 | 1 | UniProt (O75530) Pfam (PF00400) In PDB | Homo sapiens (Human) | hEED,WD protein associating with integrin cytoplasmic tails 1,WAIT-1 |
2 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
3 | A | PRASEODYMIUM ION | non-polymer | 140.9 | 1 | Chemie (PR) | |||
4 | A | 4-azanylidene-2-(3-methoxy-4-propan-2-yloxy-phenyl)-6,7-dihydro-[1,3]benzodioxolo[6,5-a]quinolizine-3-carbonitrile | non-polymer | 429.5 | 1 | Chemie (LQA) | |||
5 | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A: 76 - 441 (UniProt: O75530)
PDB | External Database | Details |
---|---|---|
Gly 66 | - | expression tag |
Ile 67 | - | expression tag |
Leu 68 | - | expression tag |
Glu 69 | - | expression tag |
Asn 70 | - | expression tag |
Leu 71 | - | expression tag |
Tyr 72 | - | expression tag |
Phe 73 | - | expression tag |
Gln 74 | - | expression tag |
Gly 75 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 43434.5 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 662.5 | |
All* | Total formula weight | 44096.9 |