5H0Y

Crystal structure of H88Y mutated human transthyretin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Transthyretin	polymer	126	14001.6	1	UniProt (P02766) Pfam (PF00576) In PDB	Homo sapiens (Human)	ATTR,Prealbumin,TBPA
2	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4		water	water		18.0	43	Chemie (HOH)

Sequence modifications

A: 11 - 127 (UniProt: P02766)

PDB	External Database	Details
Ala 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
Met 9	-	expression tag
Ser 10	-	expression tag
Tyr 88	His 108	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	14001.6
Non-Polymers*	Number of molecules	2
	Total formula weight	131.5
All*	Total formula weight	14133.1

*Water molecules are not included.