5H0X

Crystal structure of H88S mutated human transthyretin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	Transthyretin	polymer	126	13925.5	2	UniProt (P02766) Pfam (PF00576)	Homo sapiens (Human)	ATTR,Prealbumin,TBPA
2	C, D (B, A)	water	water		18.0	182	Chemie (HOH)

Sequence modifications

B, A: 11 - 127 (UniProt: P02766)

PDB	External Database	Details
Ala 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
Met 9	-	expression tag
Ser 10	-	expression tag
Ser 88	His 108	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	27851.1
All*	Total formula weight	27851.1

*Water molecules are not included.