5GZ6
Structure of D-amino acid dehydrogenase in complex with NADPH and 2-keto-6-aminocapronic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Meso-diaminopimelate D-dehydrogenase | polymer | 326 | 35881.4 | 2 | UniProt (G1UII1) | Ureibacillus thermosphaericus | Meso-DAP dehydrogenase |
| 2 | C (A) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 3 | D (A) | 6-azanyl-2-oxidanylidene-hexanoic acid | non-polymer | 145.2 | 1 | Chemie (7C3) | |||
| 4 | E, G (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | F (B) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 397 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 326 (UniProt: G1UII1)
| PDB | External Database | Details |
|---|---|---|
| Ala 94 | Asp 94 | engineered mutation |
| Leu 154 | Gln 154 | engineered mutation |
| Gly 158 | Asp 158 | engineered mutation |
| Ile 173 | Thr 173 | engineered mutation |
| Met 199 | Arg 199 | engineered mutation |
| Phe 224 | Tyr 224 | engineered mutation |
| Asn 249 | His 249 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71762.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1141.7 | |
| All* | Total formula weight | 72904.6 |
