5GZ6
Structure of D-amino acid dehydrogenase in complex with NADPH and 2-keto-6-aminocapronic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008839 | molecular_function | 4-hydroxy-tetrahydrodipicolinate reductase |
| A | 0009085 | biological_process | lysine biosynthetic process |
| A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019877 | biological_process | diaminopimelate biosynthetic process |
| A | 0047850 | molecular_function | diaminopimelate dehydrogenase activity |
| B | 0008839 | molecular_function | 4-hydroxy-tetrahydrodipicolinate reductase |
| B | 0009085 | biological_process | lysine biosynthetic process |
| B | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019877 | biological_process | diaminopimelate biosynthetic process |
| B | 0047850 | molecular_function | diaminopimelate dehydrogenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | binding site for residue NDP A 1001 |
| Chain | Residue |
| A | GLY10 |
| A | GLY70 |
| A | GLY71 |
| A | SER72 |
| A | ASP75 |
| A | SER92 |
| A | ALA94 |
| A | VAL121 |
| A | GLY122 |
| A | TRP123 |
| A | ASP124 |
| A | TYR11 |
| A | PRO125 |
| A | THR280 |
| A | 7C31002 |
| A | HOH1101 |
| A | HOH1128 |
| A | HOH1138 |
| A | HOH1253 |
| B | ARG37 |
| B | THR41 |
| B | HOH3101 |
| A | GLY12 |
| A | ASN13 |
| A | LEU14 |
| A | THR35 |
| A | ARG36 |
| A | ARG37 |
| A | CYS69 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue 7C3 A 1002 |
| Chain | Residue |
| A | ASP124 |
| A | TRP148 |
| A | LYS150 |
| A | NDP1001 |
| A | HOH1106 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 1003 |
| Chain | Residue |
| A | ASN249 |
| A | LEU273 |
| A | ASN276 |
| A | PRO277 |
| A | MET278 |
| A | PHE279 |
| A | HOH1251 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue ACT B 3001 |
| Chain | Residue |
| A | LEU130 |
| A | ASN131 |
| B | LEU127 |
| B | ASN131 |
| B | PHE310 |
| B | HOH3105 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 3002 |
| Chain | Residue |
| A | ARG37 |
| A | ASP38 |
| B | GLY12 |
| B | ARG16 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 26 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | TYR11 | |
| A | ILE173 | |
| A | MET199 | |
| A | ASN249 | |
| A | ASN276 | |
| B | TYR11 | |
| B | THR35 | |
| B | CYS69 | |
| B | SER92 | |
| B | ALA94 | |
| B | VAL121 | |
| A | THR35 | |
| B | ASP124 | |
| B | TRP148 | |
| B | LEU154 | |
| B | ILE173 | |
| B | MET199 | |
| B | ASN249 | |
| B | ASN276 | |
| A | CYS69 | |
| A | SER92 | |
| A | ALA94 | |
| A | VAL121 | |
| A | ASP124 | |
| A | TRP148 | |
| A | LEU154 |
