5GY2
Crystal structure of a complex between Bacillus subtilis flagellin and zebrafish Toll-like receptor 5
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Tlr5b protein,Variable lymphocyte receptor B | polymer | 455 | 51169.2 | 2 | UniProt (B3DIN1) UniProt (Q4G1L2) Pfam (PF13855) Pfam (PF11921) In PDB | Danio rerio (Zebrafish) | TOLL-LIKE RECEPTOR 5B |
2 | C, D | Flagellin | polymer | 183 | 19254.1 | 2 | UniProt (E0U497) Pfam (PF00669) Pfam (PF00700) In PDB | Bacillus subtilis subsp. spizizenii strain W23 | |
3 | E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
4 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
5 | A, B | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
6 | water | water | 18.0 | 465 | Chemie (HOH) |
Sequence modifications
A, B: 23 - 390 (UniProt: B3DIN1)
A, B: 391 - 465 (UniProt: Q4G1L2)
C, D: 54 - 230 (UniProt: E0U497)
PDB | External Database | Details |
---|---|---|
Ala 18 | - | expression tag |
Asp 19 | - | expression tag |
Pro 20 | - | expression tag |
Gly 21 | - | expression tag |
Thr 22 | - | expression tag |
Glu 24 | Val 24 | engineered mutation |
Val 124 | Leu 124 | engineered mutation |
Lys 159 | Gln 159 | engineered mutation |
Lys 227 | Arg 227 | engineered mutation |
Thr 229 | Ser 229 | engineered mutation |
Asn 334 | Asp 334 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 466 | - | expression tag |
Ala 467 | - | expression tag |
Ser 468 | - | expression tag |
Leu 469 | - | expression tag |
Val 470 | - | expression tag |
Pro 471 | - | expression tag |
Arg 472 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 48 | - | expression tag |
Ser 49 | - | expression tag |
Ala 50 | - | expression tag |
Lys 51 | - | expression tag |
Asp 52 | - | expression tag |
Pro 53 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 140846.8 | |
Branched | Number of molecules | 2 |
Total formula weight | 848.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1715.7 | |
All* | Total formula weight | 143411.3 |