5GW9

Crystal structure of C163, a backbone circularized G-CSF

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Granulocyte colony-stimulating factor	polymer	163	17596.3	4	UniProt (P09919) Pfam (PF16647)	Homo sapiens (Human)	G-CSF,Pluripoietin
2	E, F, G, H (A, B, C, D)	water	water		18.0	478	Chemie (HOH)

Sequence modifications

A, B, C, D: 11 - 173 (UniProt: P09919)

PDB	External Database	Details
Ser 11	Pro 40	engineered mutation
Ser 18	Cys 47	engineered mutation
Gly 173	Ala 202	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	70385.0
All*	Total formula weight	70385.0

*Water molecules are not included.