5GTC

Crystal structure of complex between DMAP-SH conjugated with a Kaposi's sarcoma herpesvirus LANA peptide (5-15) and nucleosome core particle

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E	Histone H3.1	polymer	139	15719.4	2	UniProt (P68431) Pfam (PF00125) In PDB	Homo sapiens (Human)
2	B, F	Histone H4	polymer	106	11676.7	2	UniProt (P62805) Pfam (PF15511) In PDB	Homo sapiens (Human)
3	C, G	Histone H2A type 1-B/E	polymer	133	14447.8	2	UniProt (P04908) Pfam (PF00125) Pfam (PF16211) In PDB	Homo sapiens (Human)
4	D, H	Histone H2B type 1-J	polymer	129	14217.5	2	UniProt (P06899) Pfam (PF00125) In PDB	Homo sapiens (Human)
5	I, J	DNA (146-MER)	polymer	146	45053.9	2		Homo sapiens (Human)
6	K	LANA peptide	polymer	12	1178.4	1	UniProt (D0UZU1) UniProt (by SIFTS) (Q9QR71) In PDB	Human herpesvirus 8
7	A, C, E, G	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
8	E, I, J	MANGANESE (II) ION	non-polymer		54.9	6	Chemie (MN)

Sequence modifications

A, E: 0 - 135 (UniProt: P68431)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

B, F: 0 - 102 (UniProt: P62805)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

C, G: 0 - 129 (UniProt: P04908)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

D, H: 0 - 125 (UniProt: P06899)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

K: 5 - 15 (UniProt: D0UZU1)

PDB	External Database	Details
Nh2 16	-	amidation

Contents of the asymmetric unit

Polymers	Number of chains	11
	Total formula weight	203409.1
Non-Polymers*	Number of molecules	10
	Total formula weight	471.4
All*	Total formula weight	203880.5

*Water molecules are not included.