5GSN

Tmm in complex with methimazole

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Flavin-containing monooxygenase	polymer	453	51686.6	4	UniProt (A3SLM3) Pfam (PF00743) In PDB	Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM)
2	A, B, C, D	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	4	Chemie (NAP)
3	A, B, C, D	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	4	Chemie (FAD)
4	A, C	1-METHYL-1,3-DIHYDRO-2H-IMIDAZOLE-2-THIONE	non-polymer		114.2	2	Chemie (MMZ)
5		water	water		18.0	786	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 447 (UniProt: A3SLM3)

PDB	External Database	Details
Ala 153	Glu 153	engineered mutation
Ala 154	Asp 154	engineered mutation
Ser 207	Tyr 207	engineered mutation
His 448	-	expression tag
His 449	-	expression tag
His 450	-	expression tag
His 451	-	expression tag
His 452	-	expression tag
His 453	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	206746.4
Non-Polymers*	Number of molecules	10
	Total formula weight	6344.2
All*	Total formula weight	213090.5

*Water molecules are not included.