5GSN
Tmm in complex with methimazole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Flavin-containing monooxygenase | polymer | 453 | 51686.6 | 4 | UniProt (A3SLM3) Pfam (PF00743) | Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM) | |
| 2 | E, H, J, M (A, B, C, D) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) | |||
| 3 | F, I, K, N (A, B, C, D) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 4 | G, L (A, C) | 1-METHYL-1,3-DIHYDRO-2H-IMIDAZOLE-2-THIONE | non-polymer | 114.2 | 2 | Chemie (MMZ) | |||
| 5 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 786 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 447 (UniProt: A3SLM3)
| PDB | External Database | Details |
|---|---|---|
| Ala 153 | Glu 153 | engineered mutation |
| Ala 154 | Asp 154 | engineered mutation |
| Ser 207 | Tyr 207 | engineered mutation |
| His 448 | - | expression tag |
| His 449 | - | expression tag |
| His 450 | - | expression tag |
| His 451 | - | expression tag |
| His 452 | - | expression tag |
| His 453 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 206746.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 6344.2 | |
| All* | Total formula weight | 213090.5 |
