5GS5

Crystal structure of apo rat STING

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Stimulator of interferon genes protein	polymer	225	25324.4	4	UniProt (F1M391) Pfam (PF15009)	Rattus norvegicus (Rat)	rSTING,Transmembrane protein 173
2	E, F, G, H, I... (A, B, C, D)	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
3	N, O, P, Q (A, B, C, D)	water	water		18.0	600	Chemie (HOH)

Sequence modifications

A, B, C, D: 140 - 337 (UniProt: F1M391)

PDB	External Database	Details
Met 117	-	expression tag
Gly 118	-	expression tag
Ser 119	-	expression tag
Ser 120	-	expression tag
His 121	-	expression tag
His 122	-	expression tag
His 123	-	expression tag
His 124	-	expression tag
His 125	-	expression tag
His 126	-	expression tag
Ser 127	-	expression tag
Ser 128	-	expression tag
Gly 129	-	expression tag
Glu 130	-	expression tag
Asn 131	-	expression tag
Leu 132	-	expression tag
Tyr 133	-	expression tag
Phe 134	-	expression tag
Gln 135	-	expression tag
Gly 136	-	expression tag
Ser 137	-	expression tag
His 138	-	expression tag
Met 139	-	expression tag
Ala 338	-	expression tag
Ala 339	-	expression tag
Ala 340	-	expression tag
Ala 341	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	101297.7
Non-Polymers*	Number of molecules	9
	Total formula weight	864.6
All*	Total formula weight	102162.3

*Water molecules are not included.