5GRM
Crystal structure of rat STING in complex with cyclic GMP-AMP with 2'5'and 3'5'phosphodiester linkage(2'3'-cGAMP)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Stimulator of interferon genes protein | polymer | 210 | 23935.9 | 2 | UniProt (F1M391) Pfam (PF15009) In PDB | Rattus norvegicus (Rat) | rSTING,Transmembrane protein 173 |
2 | B | cGAMP | non-polymer | 674.4 | 1 | Chemie (1SY) | |||
3 | water | water | 18.0 | 406 | Chemie (HOH) |
Sequence modifications
A, B: 155 - 341 (UniProt: F1M391)
PDB | External Database | Details |
---|---|---|
Met 132 | - | expression tag |
Gly 133 | - | expression tag |
Ser 134 | - | expression tag |
Ser 135 | - | expression tag |
His 136 | - | expression tag |
His 137 | - | expression tag |
His 138 | - | expression tag |
His 139 | - | expression tag |
His 140 | - | expression tag |
His 141 | - | expression tag |
Ser 142 | - | expression tag |
Ser 143 | - | expression tag |
Gly 144 | - | expression tag |
Glu 145 | - | expression tag |
Asn 146 | - | expression tag |
Leu 147 | - | expression tag |
Tyr 148 | - | expression tag |
Phe 149 | - | expression tag |
Gln 150 | - | expression tag |
Gly 151 | - | expression tag |
Ser 152 | - | expression tag |
His 153 | - | expression tag |
Met 154 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 47871.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 674.4 | |
All* | Total formula weight | 48546.2 |