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5GRH

Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrialpolymer33936682.21UniProt (P50213)
Pfam (PF00180)
Homo sapiens (Human)Isocitric dehydrogenase subunit alpha,NAD(+)-specific ICDH subunit alpha
2B
(B)
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrialpolymer35438867.51UniProt (P51553)
Pfam (PF00180)
Homo sapiens (Human)Isocitric dehydrogenase subunit gamma,NAD(+)-specific ICDH subunit gamma
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight75549.7
Non-Polymers*Number of molecules1
Total formula weight24.3
All*Total formula weight75574.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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