5GP1
Crystal structure of ZIKV NS5 Methyltransferase in complex with GTP and SAH
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | RNA-directed RNA polymerase NS5 | polymer | 269 | 29711.9 | 3 | UniProt (H9A910) Pfam (PF01728) UniProt (by SIFTS) (A0A024B7W1) In PDB | Zika virus (ZIKV) | NS5 Methyltransferase |
2 | A, B, C | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
3 | A, B, C | P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE | non-polymer | 787.4 | 3 | Chemie (GTA) | |||
4 | A, B, C | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 3 | Chemie (SAH) | |||
5 | C | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
6 | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A, B, C: 4 - 265 (UniProt: H9A910)
PDB | External Database | Details |
---|---|---|
Gly 0 | - | expression tag |
Ser 1 | - | expression tag |
Val 2 | - | expression tag |
Asp 3 | - | expression tag |
Ala 266 | - | expression tag |
Ala 267 | - | expression tag |
Ser 268 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 89135.7 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 4342.8 | |
All* | Total formula weight | 93478.5 |