5GO3

Crystal structure of a di-nucleotide cyclase Vibrio mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Cyclic GMP-AMP synthase	polymer	447	50669.5	2	UniProt (Q9KVG7) Pfam (PF21654) Pfam (PF21713)	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	c-GMP-AMP synthase,3'3'-cGAMP synthase,Cyclic AMP-GMP synthase,c-AMP-GMP synthase,Dinucleotide cyclase DncV
2	C, D (A, B)	water	water		18.0	278	Chemie (HOH)

Sequence modifications

A, B: 1 - 436 (UniProt: Q9KVG7)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Asn 131	Asp 131	engineered mutation
Asn 133	Asp 133	engineered mutation
His 437	-	expression tag
His 438	-	expression tag
His 439	-	expression tag
His 440	-	expression tag
His 441	-	expression tag
His 442	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	101339.0
All*	Total formula weight	101339.0

*Water molecules are not included.