5GNS
Structures of human Mitofusin 1 provide insight into mitochondrial tethering
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mitofusin-1 | polymer | 421 | 47334.8 | 1 | UniProt (Q8IWA4) Pfam (PF00350) In PDB | Homo sapiens (Human) | Fzo homolog,Transmembrane GTPase MFN1 |
| 2 | A | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 3 | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: 1 - 364 (UniProt: Q8IWA4)
| PDB | External Database | Details |
|---|---|---|
| Ala 88 | Lys 88 | engineered mutation |
| Gly 365 | - | expression tag |
| Ser 366 | - | expression tag |
| Gly 367 | - | expression tag |
| Ser 368 | - | expression tag |
| Gly 369 | - | expression tag |
| Ser 370 | - | expression tag |
| Gly 371 | - | expression tag |
| Gly 372 | - | expression tag |
| Ser 373 | - | expression tag |
| Glu 374 | - | expression tag |
| Ile 375 | - | expression tag |
| Ala 376 | - | expression tag |
| Arg 377 | - | expression tag |
| Leu 378 | - | expression tag |
| Pro 379 | - | expression tag |
| Lys 380 | - | expression tag |
| Glu 381 | - | expression tag |
| Ile 382 | - | expression tag |
| Asp 383 | - | expression tag |
| Gln 384 | - | expression tag |
| Leu 385 | - | expression tag |
| Glu 386 | - | expression tag |
| Lys 387 | - | expression tag |
| Ile 388 | - | expression tag |
| Gln 389 | - | expression tag |
| Asn 390 | - | expression tag |
| Asn 391 | - | expression tag |
| Ser 392 | - | expression tag |
| Lys 393 | - | expression tag |
| Leu 394 | - | expression tag |
| Leu 395 | - | expression tag |
| Arg 396 | - | expression tag |
| Asn 397 | - | expression tag |
| Lys 398 | - | expression tag |
| Ala 399 | - | expression tag |
| Val 400 | - | expression tag |
| Gln 401 | - | expression tag |
| Leu 402 | - | expression tag |
| Glu 403 | - | expression tag |
| Asn 404 | - | expression tag |
| Glu 405 | - | expression tag |
| Leu 406 | - | expression tag |
| Glu 407 | - | expression tag |
| Asn 408 | - | expression tag |
| Phe 409 | - | expression tag |
| Thr 410 | - | expression tag |
| Lys 411 | - | expression tag |
| Gln 412 | - | expression tag |
| Phe 413 | - | expression tag |
| Leu 414 | - | expression tag |
| Pro 415 | - | expression tag |
| Ser 416 | - | expression tag |
| Ser 417 | - | expression tag |
| Asn 418 | - | expression tag |
| Glu 419 | - | expression tag |
| Glu 420 | - | expression tag |
| Ser 421 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47334.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 523.2 | |
| All* | Total formula weight | 47858.0 |
