5GN8

Structure of a 48-mer protein nanocage fabricated from its 24-mer analogue by subunit interface redesign

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Ferritin heavy chain	polymer	176	20453.7	1	UniProt (P02794) Pfam (PF00210) In PDB	Homo sapiens (Human)	Ferritin H subunit,Cell proliferation-inducing gene 15 protein
2	B	Ferritin heavy chain	polymer	146	17171.2	1	UniProt (P02794) Pfam (PF00210) In PDB	Homo sapiens (Human)	Ferritin H subunit,Cell proliferation-inducing gene 15 protein
3	A, B	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4		water	water		18.0	2	Chemie (HOH)

Sequence modifications

A: 1 - 176 (UniProt: P02794)

PDB	External Database	Details
-	Asn 140	deletion
-	Glu 141	deletion
-	Gln 142	deletion
-	Val 143	deletion
-	Lys 144	deletion
-	Ala 145	deletion

B: 1 - 146 (UniProt: P02794)

PDB	External Database	Details
-	Asn 140	deletion
-	Glu 141	deletion
-	Gln 142	deletion
-	Val 143	deletion
-	Lys 144	deletion
-	Ala 145	deletion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	37624.9
Non-Polymers*	Number of molecules	2
	Total formula weight	80.2
All*	Total formula weight	37705.0

*Water molecules are not included.