5GJI
PI3K p85 N-terminal SH2 domain/CD28-derived peptide complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Phosphatidylinositol 3-kinase regulatory subunit alpha | polymer | 108 | 12433.0 | 1 | UniProt (P27986) Pfam (PF00017) In PDB | Homo sapiens (Human) | PtdIns-3-kinase regulatory subunit alpha,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,PtdIns-3-kinase regulatory subunit p85-alpha |
2 | B | T-cell-specific surface glycoprotein CD28 | polymer | 8 | 1038.0 | 1 | UniProt (P10747) In PDB | Homo sapiens | TP44 |
3 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 325 - 430 (UniProt: P27986)
PDB | External Database | Details |
---|---|---|
Gly 323 | - | expression tag |
Ser 324 | - | expression tag |
Asn 330 | Asp 330 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 13471.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 380.3 | |
All* | Total formula weight | 13851.3 |